The two major forms of vitamin B6 are pyridoxine and pyridoxamine. In the liver they
are converted to pyridoxal 5'-phosphate (PLP) which is a cofactor in many reactions
of amino acid metabolism. PLP also is necessary for the enzymatic reaction governing
the release of glucose from glycogen.
Pyroluria is one potential cause of vitamin B6 deficiency. An overdose of pyridoxine
can cause a temporary deadening of certain nerves such as the proprioceptory nerves;
causing a feeling of dissembodiment common with the loss of proprioception
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